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February 10, 2012

Pleural Effusion

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Pleural Effusion

Pleural Effusion Symptoms and Signs

The most common symptom of pleural effusion is shortness of breath or difficulty breathing. As the effusion grows larger the more difficult it is for the person to breathe.

Chest pain is also a symptom of pleural effusion and occurs because the pleural lining of the lung is irritated. The pain is usually described as a sharp pain, worsening with a deep breath. As the pleural effusion increases in size, the pain also may increase.

Other associated symptoms of pleural effusion are due to the underlying disease. For example, a person with congestive heart failure may have signs and symptoms of feet swelling and shortness of breath while laying flat. Someone with pneumonia may have a fever, chills, and a cough that produces colored sputum and pleural pain.

What is pleural effusion?

A pleural effusion is a collection of fluid in the space between the two linings (pleura) of the lung.

When we breathe, it is like a bellows. We inhale air into our lungs and the ribs move out and the diaphragm moves down. For the lung to expand, its lining has to slide along with the chest wall movement. For this to happen, both the lungs and the ribs are covered with a slippery lining called the pleura. A small amount of fluid acts as a lubricant for these two surfaces to slide easily against each other.

Too much fluid impairs the ability of the lung to expand and move.

Picture of pleural effusion

What causes pleural effusion?

A pleural effusion is not normal. It is not a disease but rather a complication of an underlying illness. Extra fluid (effusion) can occur for a variety of reasons. Common classification systems divide pleural effusions based on the chemistry composition of the fluid and what causes the effusion to be formed. Two classifications are 1) transudate pleural effusions; and 2) exudate pleural effusions. Sometimes the pleural effusion can have characteristics of both a transudate and an exudate.

1. Transudate pleural effusions are formed when fluid leaks from blood vessels into the pleural space. Chemically, transudate pleural effusions contain less protein and LDH (lactate dehydrogenase) than exudate pleural effusions. If both the pleural fluid–to–serum total protein ratio is less than or equal to 0.50 and the pleural fluid–to–serum LDH ratios are less than or equal to 0.67, the fluid is usually considered to be a transudate while exudates ratios are above 0.50 and above 0.67.

Examples of transudate pleural effusions include:

2. Exudate pleural effusions are caused by inflammation of the pleura itself and are often due to disease of the lung.

Examples of exudate causes include:

Most pleural effusions are caused by congestive heart failure, pneumonia, pulmonary embolism and malignancy.



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Pleural Effusion

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