piroxicam, Feldene (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
Alcohol consumption may increase the risk of developing stomach ulcers when taking piroxicam or other NSAIDs.
PREGNANCY: Safety during pregnancy has not been established. Use in late pregnancy may cause premature closing of the ductus arteriosus in the fetus.
NURSING MOTHERS: Piroxicam is excreted into human breast milk. Use by nursing mothers is not recommended.
SIDE EFFECTS: The most common side effects of piroxicam are rash, headaches, dizziness, drowsiness, abdominal pain, nausea, constipation, fluid retention, ringing in the ears, and photosensitivity. NSAIDs reduce the ability of blood to clot and therefore increase bleeding after an injury. Piroxicam also may cause stomach and intestinal bleeding and ulcers. Sometimes, stomach ulceration and intestinal bleeding can occur without any abdominal pain. Black tarry stools, weakness, and dizziness upon standing may be the only signs of the bleeding. People who are allergic to other NSAIDs should not use piroxicam. NSAIDs reduce the flow of blood to the kidneys and impair function of the kidneys. The impairment is most likely to occur in patients with preexisting impairment of kidney function or congestive heart failure, and use of NSAIDs in these patients should be done cautiously. Individuals with asthma are more likely to experience allergic reactions to prioxicam and other NSAIDs. Fluid retention, blood clots, heart attacks, hypertension, and heart failure have also been associated with the use of NSAIDs.
Reference: FDA Prescribing Information
Last Editorial Review: 1/6/2012
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