pimecrolimus, Elidel (cont.)

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Medical and Pharmacy Editor:

Other important side effects include:

Skin cancer and lymphoma have rarely occurred during treatment with pimecrolimus. Therefore, pimecrolimus should not be used for long-term treatment and should only be applied to affected areas.

PRESCRIPTION: Yes

GENERIC AVAILABLE: No

PREPARATIONS: Cream, 1%

STORAGE: Pimecrolimus should be stored at room temperature, 15 C - 30 C (59 F - 86 F).

DOSING: Patients should completely rub in a thin layer of pimecrolimus to the affected areas twice daily. An improvement in symptoms can be seen within 8-15 days, and patients should contact their physician if there is no response after six weeks of use.

DRUG INTERACTIONS: Interactions between pimecrolimus and other drugs have not been studied. Since very little pimecrolimus is absorbed from the skin, drug interactions are not expected. However, since some pimecrolimus is absorbed, caution should be exercised when pimecrolimus is used by individuals also taking drugs (for exmaple, ketoconazole [Nizoral, Extina, Xolegel, Kuric], itraconazole [Sporanox], erythromycin, fluconazole [Diflucan], calcium channel blockers [CCBs], cimetidine [Tagamet]) that inhibit the liver enzymes that eliminate pimecrolimus and could increase the levels of pimecrolimus and promote its toxicity.

PREGNANCY: There are no adequate studies that evaluate the use of pimecrolimus during pregnancy.

Medically Reviewed by a Doctor on 7/23/2015


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