pimecrolimus, Elidel (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PRESCRIBED FOR: Pimecrolimus is used for the short-term treatment of mild to moderate atopic dermatitis in individuals who are two years of age or older and who cannot use or have failed to respond to other therapies. Pimecrolimus should not be used by individuals with a weakened immune system.

SIDE EFFECTS: The most common side effects of pimecrolimus are:

  • reactions at the site of application,
  • burning,
  • itching, and
  • redness.

Other important side effects include:

Skin cancer and lymphoma have rarely occurred during treatment with pimecrolimus. Therefore, pimecrolimus should not be used for long-term treatment and should only be applied to affected areas.




STORAGE: Pimecrolimus should be stored at room temperature, 15 C - 30 C (59 F - 86 F).

DOSING: Patients should completely rub in a thin layer of pimecrolimus to the affected areas twice daily. An improvement in symptoms can be seen within 8-15 days, and patients should contact their physician if there is no response after six weeks of use.

DRUG INTERACTIONS: Interactions between pimecrolimus and other drugs have not been studied. Since very little pimecrolimus is absorbed from the skin, drug interactions are not expected. However, since some pimecrolimus is absorbed, caution should be exercised when pimecrolimus is used by individuals also taking drugs (for exmaple, ketoconazole [Nizoral, Extina, Xolegel, Kuric], itraconazole [Sporanox], erythromycin, fluconazole [Diflucan], calcium channel blockers [CCBs], cimetidine [Tagamet]) that inhibit the liver enzymes that eliminate pimecrolimus and could increase the levels of pimecrolimus and promote its toxicity.

Medically Reviewed by a Doctor on 7/23/2015

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