Are there any interactions with medications?

Medications that decrease the immune system (Immunosuppressants)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Picrorhiza might increase the activity of the immune system. Taking picrorhiza along with medications that decrease the activity of the immune system might decrease the effectiveness of these medications.

Some medications that decrease the activity of the immune system include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and others.

Dosing considerations for Picrorhiza.

The following doses have been studied in scientific research:

  • For a disease called vitiligo that causes white patches on the skin: 200 mg of picrorhiza rhizome powder twice a day, in combination with a medication called methoxsalen that is taken by mouth and applied to the affected skin.

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Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.