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Phlebitis and Thrombophlebitis (cont.)

How is phlebitis diagnosed?

The diagnosis of superficial phlebitis can be made based on the physical examination by a physician. Warmth, tenderness, redness, and swelling along the course of the vein is highly suggestive of superficial phlebitis or thrombophlebitis. An ultrasound of the area can help in making the diagnosis of phlebitis or excluding it.

D-dimer is a useful blood test that can suggest phlebitis. This is a chemical that is released by blood clots when they start to degrade. A normal D-dimer makes the diagnosis of thrombophlebitis unlikely. The limitation of this test is its lack of specificity, meaning that an elevated D-dime level can be seen in other conditions including recent surgery, fall, pregnancy, or an underlying cancer.

Conditions that mimic phlebitis include cellulitis (superficial skin infection), insect bites, or lymphangitis (swelling and inflammation of lymph nodes) and can be distinguished by obtaining a careful medical history and physical examination by a physician. Sometimes, a biopsy of the skin may be required to establish the definite diagnosis.

How is phlebitis treated?

Treatment of phlebitis may depend on the location, extent, symptoms, and underlying medical conditions.

In general, superficial phlebitis of the upper and lower extremities can be treated by applying warm compresses, elevation of the involved extremity, encouraging ambulation (walking), and oral anti-inflammatory medications [ibuprofen (Motrin, Advil), diclofenac (Voltaren, Cataflam, Voltaren-XR), etc.]. Topical anti-inflammatory medications may also be beneficial, such as diclofenac gel. External compression with fitted stockings is also a recommended for patients with superficial phlebitis of the lower extremities.

If an intravenous catheter is the cause, then it should be removed. If the phlebitis is infected, then antibiotics are used. In severe cases of infected thrombophlebitis, surgical exploration may be necessary.

Superficial thrombophlebitis (blood clots) is evaluated by an ultrasound to exclude deep venous thrombophlebitis, especially those involving the saphenous vein. If deep venous thrombophlebitis is suspected or diagnosed, or if its risk of developing is considerable, then anti-coagulation (thinning of blood) may be necessary. This is typically done by injection of low molecular weight heparin [enoxaparin  (Lovenox)] followed by oral anti-coagulation with warfarin (Coumadin) for about 3 to 6 months.

Recovery of symptoms from superficial phlebitis can last a few weeks. A thrombophlebitis may take weeks to months to recover.



Next: What are the complications of phlebitis? »

Phlebitis

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