phenytoin, Dilantin, Dilantin Infatabs, Phenytek, Phenytoin Infatabs

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

GENERIC NAME: phenytoin

BRAND NAME: Dilantin, Dilantin Infatabs, Phenytek, Phenytoin Infatabs

DISCONTINUED BRAND: Dilantin-125

DRUG CLASS AND MECHANISM: Phenytoin is an oral and injectable anti-seizure medication first synthesized in 1908. The exact mechanism of action is not known, Phenytoin may work by reducing the sensitivity of nerves in the brain to excessive stimulation and reducing transmission of impulses between nerves. Phenytoin was originally approved by the FDA in 1939.

PRESCRIBED FOR: Phenytoin is an anti-seizure medication (anticonvulsant) used for preventing or treating generalized tonic-clonic (grand mal) seizures, complex partial seizures (psychomotor seizures), and seizures occurring during or after neurosurgery. It may be used alone or with phenobarbital or other anticonvulsants.

SIDE EFFECTS: Many adverse effects can occur during phenytoin therapy including:

Children and young adults can develop overgrowth of the gums during long-term therapy which requires regular treatment by a dentist. Good oral hygiene and gum massage may reduce the risk. R

Medically Reviewed by a Doctor on 1/28/2015

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