phenylephrine hydrochloride (NeoSynephrine, Neofrin)

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Phenylephrine should be used with caution with antidepressants like amitriptyline (Elavil, Endep), nortriptyline (Pamelor, Aventyl), doxepin (Sinequan, Adapin), and trazodone (Deyrel). Such anti-depressants may increase blood pressure if used together with phenylephrine.

PREGNANCY: There are no adequate studies done on phenylephrine to determine safe and effective use in pregnant women.

NURSING MOTHERS: It is not known whether phenylephrine enters breast milk; therefore, it is best to be cautious before using it in nursing mothers.

SIDE EFFECTS: Side effects of phenylephrine are headache, reflex bradycardia (slow heart beat), excitability, anxiety, restlessness, high blood pressure, and rarely abnormal heart beats.

REFERENCES:

FDA Prescribing Information.

Medscape. phenylephrine.

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