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- What is phenylbutazone, and how does it work (mechanism of action)?
- What brand names are available for phenylbutazone?
- Is phenylbutazone available as a generic drug?
- Do I need a prescription for phenylbutazone?
- What are the side effects of phenylbutazone?
- What is the dosage for phenylbutazone?
- Which drugs or supplements interact with phenylbutazone?
- Is phenylbutazone safe to take if I'm pregnant or breastfeeding?
- What else should I know about phenylbutazone?
What is the dosage for phenylbutazone?
Should be taken with food.
Which drugs or supplements interact with phenylbutazone?
Phenylbutazone should be avoided by patients with a history of asthma attacks, hives, or other allergic reactions to aspirin or other NSAIDs. Rare but severe allergic reactions have been reported in such individuals. It also should be avoided by patients with peptic ulcer disease or poor kidney function, since this medication can aggravate both conditions. Phenylbutazone is generally used with caution in patients taking blood thinning medications (anticoagulants), such as warfarin (Coumadin), because of an increased risk of bleeding. Patients taking lithium (Eskalith, Lithobid) can develop toxic blood lithium levels. Additionally, patients taking cyclosporine (Sandimmune) can develop kidney toxicity. Use in children has not been adequately studied. Phenylbutazone is not habit forming. NSAIDs should be discontinued prior to elective surgery because of a mild interference with clotting that is characteristic of this group of medicines. Phenylbutazone is best discontinued at least three days in advance of the procedure.
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