phentermine (Adipex-P, Obenix, Suprenza) (cont.)

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PREPARATIONS: Tablets: 30 and 37.5mg.; Orally disintegrating tablets: 15, 30, 37.5 mg.

STORAGE: Phentermine should be stored in a tight container at room temperature, 20 C to 25 C (68 F to 77 F).

DOSING: The recommended dose is 15-37.5 mg once daily. Adipex-P is administered about 1-2 hours after breakfast. The lowest effective dose should be used and evening doses should be avoided because phentermine causes insomnia.

DRUG INTERACTIONS: Phentermine is similar to amphetamine and may share some of the interactions associated with amphetamines. Combining phentermine with tricyclic antidepressants (for example, amitriptyline [Elavil, Endep]) or monoamine oxidase inhibitors or MAOIs (for example, phenelzine [Nardil], selegiline [Zelapar, Emsam, and Eldepryl], tranylcypromine [Parnate]) may result in high blood pressure and other serious reactions because of elevated serotonin levels in the blood. Phentermine should not be used within 14 days after stopping a monoamine oxidase inhibitor.

People with with diabetes being treated with phentermine may require a reduction in their dose of insulin or oral hypoglycemic drug.

PREGNANCY: Use of phentermine during pregnancy has not been adequately evaluated.

NURSING MOTHERS: It is not known whether phentermine is excreted in human breast milk. Since other amphetamines are excreted in breast milk, phentermine should not be used while breastfeeding or, if used, nursing should be discontinued.

Reference: FDA Prescribing Information

Medically Reviewed by a Doctor on 9/18/2015

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