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- What are phenothiazine antipsychotics?
- What are examples of phenothiazine antipsychotics available in the US?
- What are the side effects of phenothiazine antipsychotics?
- What drugs interact with phenothiazine antipsychotics?
- What formulations of phenothiazine antipsychotics are available?
- What about taking phenothiazine antipsychotics during pregnancy or while breastfeeding?
What are phenothiazine antipsychotics?
Phenothiazine antipsychotics are medications used to treat schizophrenia and manifestations of psychotic disorders. Some phenothiazine antipsychotics, like prochlorperazine and chlorpromazine, are used for nausea, vomiting, and hiccups.
Although, the exact mechanism of phenothiazine antipsychotics is unknown, scientists believe that they may work by blocking the action of dopamine in the brain. Dopamine is a neurotransmitter (chemical) that nerves use to communicate with one another. Phenothiazine antipsychotics are used when patients do not respond to other antipsychotics.
What are examples of phenothiazine antipsychotics available in the US?
Examples of phenothiazine antipsychotics are:
- prochlorperazine (Compazine, Compro, Procomp),
- chlorpromazine (Promapar, Thorazine),
- fluphenazine (Permitil, Prolixin),
- trifluoperazine (Stelazine),
- thioridazine (Mellaril), and
- mesoridazine (no longer available in the United States).
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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