Peyronie's Disease (Curvature of the Penis)

  • Medical Author:
    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

  • Medical Editor: Jerry R. Balentine, DO, FACEP
    Jerry R. Balentine, DO, FACEP

    Jerry R. Balentine, DO, FACEP

    Dr. Balentine received his undergraduate degree from McDaniel College in Westminster, Maryland. He attended medical school at the Philadelphia College of Osteopathic Medicine graduating in1983. He completed his internship at St. Joseph's Hospital in Philadelphia and his Emergency Medicine residency at Lincoln Medical and Mental Health Center in the Bronx, where he served as chief resident.

Penile Pain Causes and Symptoms

Penile pain may be caused by:

  • STDs with symptoms of burning, itching, painful urination, discharge, or blood in the urine
  • Infections or inflammation such as balantis
  • Persistent erection (priapism)
  • Peyronie's disease
  • Cancers

Peyronie's disease facts

  • Peyronie's disease is the development of scar tissue inside the penis that results in abnormal curvature of the penis.
  • The exact cause of Peyronie's disease is not known; however, research has suggested these agents as possible causes of plaque or scar formation in the penile shaft.
  • Some of the symptoms of Peyronie's disease include:
  • Peyronie's disease is diagnosed by physical examination of the penis that shows abnormal curvature and plaque/scar formation that may be palpated.
  • There is no cure for Peyronie's disease; however, symptoms can be treated with vitamins, supplements, and other medications.
  • Complications of the disease include pain with intercourse, inability to have intercourse, erectile dysfunction, depression and a permanent abnormal angulation of the penis
  • The prognosis of Peyronie's disease varies from good to poor, depending on the individual's response to treatments

What is Peyronie's disease?

Peyronie's disease (also termed Peyronie disease) is the development of scar tissue inside the penis that causes the penis to develop abnormal curvature (contracture) in the scarred area. The disease may occur in about 1% to 8% of men, most frequently in men aged about 40 to 70 years old. The disease also may occur more frequently with men that develop:

It occasionally can occur in younger men.

What causes Peyronie's disease?

The exact cause of Peyronie's disease is not known. However, whatever can cause plaque or scar formation in the penile shaft is a likely causal candidate. Researchers have suggested several possible agents such as vitamin E deficiency, beta-blocking medications, elevations in serotonin, and genetic causes. Some researchers think that minor vascular traumas to the penis (during sex, athletic or exercise endeavors) that occur repeatedly over time may lead to scar formation. None of these possible agents or processes is proven to be the cause to date.

Medically Reviewed by a Doctor on 9/6/2016

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