Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.
Dr. Balentine received his undergraduate degree from McDaniel College in Westminster, Maryland. He attended medical school at the Philadelphia College of Osteopathic Medicine graduating in1983. He completed his internship at St. Joseph's Hospital in Philadelphia and his Emergency Medicine residency at Lincoln Medical and Mental Health Center in the Bronx, where he served as chief resident.
Peyronie's disease (also termed Peyronie disease) is the development of scar
tissue inside the penis that causes the penis to develop abnormal curvature
(contracture) in the scarred area. The disease may occur in about 1% to 8% of men,
most frequently in men aged about 40 to 70 years old. It can occasionally occur
in younger men.
The exact cause of Peyronie's disease is not known. However, whatever can
cause plaque or scar formation in the penile shaft is a likely causal candidate.
Researchers have suggested several possible agents such as vitamin E deficiency,
beta-blocking medications, elevations in serotonin, and
genetic causes. Some
researchers think that minor vascular traumas to the penis (during sex or
athletic endeavors) that may reoccur over time may lead to scar formation. None
of these possible agents or processes is proven to be the cause to date.
There are, in general, two phases of the disease. The acute phase lasts about
18 to 24 months and usually has the highest pain component; the chronic phase
(begins at about 18 to 24 months after first symptoms) usually has less pain but
in this stage, the plaque or scarring is more refractory to treatment (see
below) and may begin to develop large calcium deposits (calcified plaque or