Patient Comments: Pernicious Anemia - Symptoms

The symptoms of pernicious anemia can vary greatly from patient to patient. What were your symptoms at the onset of your disease?

Comment from: 55-64 Female (Patient) Published: October 15

My grandfather had pernicious anemia and so did my mother, an aunt, and an uncle. I have all the symptoms, but my doctor says my B12 is not low. My levels have not been checked since March of this year. It was 334. This is low normal. I have read that sometimes intrinsic factor must be checked to get a correct diagnosis. I feel so tired all the time. My hemoglobin did show up to be low. It was 10, but my doctor did not put me on iron.

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Comment from: juliea, 65-74 Female (Patient) Published: May 21

I have colitis diagnosed 2 years ago; since then have lost balance, have fallen, and am clumsy walking. My ankles hurt and are easily injured, can"t exercise the way I want. I have peripheral neuropathy and am extremely tired. Every symptom falls within the list for pernicious anemia. I had a B12 and folate level drawn yesterday, so now have to wait. Good luck to you all.

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Comment from: Lolac, 35-44 Female (Patient) Published: April 11

I"ve had severe reaction to coldness, muscle pain, extreme fatigue, lack of concentration, pain in arms which feels like nerve damage and more recently dizziness. I got B12 checked which showed 164, the general physician said although it was low he didn"t feel the need to treat it as the symptoms were attributed to another medication I take for ulcerative colitis and arthritis. I explained I had experienced these symptoms before I began the medication. Having read many case studies on the pernicious anemia site I"m convinced that is the problem. I am only 37 and my quality of life is terrible, I"m so tired and this is not good as I"m a mother of a two year old.

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Comment from: Katie, 65-74 Female (Patient) Published: October 24

I was diagnosed with pernicious anemia in my late forties. I was walking with a friend and could barely walk up a slight slope without sitting on a wall for a rest. I had felt tired at times and tingling in my feet and hands sometimes but I was a busy person so just thought I needed to slow down a bit. However that day worried me as I had never been that tired before. My general physician checked my reflexes which were okay and decided to take a blood sample. She sent for me a few days later to do some more tests and found I had a low B12 level so ended up being diagnosed with pernicious anemia. When I saw the specialist, he took one look at me and said I had all the classic symptoms before he even diagnosed me! Once I learned more about it I realized I may have had it for years without knowing! I had low blood count especially after giving birth to my two daughters and I also had 4 miscarriages at 3 months each time, and could have no more children. There were other times I was ill not knowing what was wrong, I had loss of balance, etc.

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Comment from: christopher, 65-74 Male (Patient) Published: October 15

I am a male, 69 years old, and was diagnosed with chronic obstructive pulmonary disease (COPD) in 2010. I could hardly do anything that needed effort due to my breathing. I had numerous things going wrong, e.g., dizziness, slurred speech, tingling fingers, and a very sore tongue. Everything was COPD I was told. It wasn't till I went to Greece in 2013, I collapsed and rushed to hospital where I required 5 units of blood, I was told I had severe pernicious anemia and had been severely neglected for about 3 years. I had very little B12 in my body and my hemoglobin level was 4.4 - severely dangerous. Now I am home and being treated properly my COPD has magically gone. I get short of breath sometimes but I know now its caused by pernicious anemia.

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Published: August 07

I started having severe abdominal cramping two nights ago and which was preceded by constipation for two days. When I woke up the following more of the beginning of the cramping I felt OK, but then by the afternoon I ate lunch and started having severe diarrhea. Now the cramping has been going on for two days and I can't keep anything in my stomach. I have been diagnosed with IBS in the past along with anemia, but with my IBS I don't normally have the cramping.

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Comment from: MightyWeak, 35-44 Female (Patient) Published: August 25

I am 44 years old and have just been diagnosed with pernicious anemia. My B12 level was at the bottom of the barrel on the chart on my blood test. My symptoms began vaguely but then quickly got worse as time went on. I am extremely fatigued and my muscles hurt. I have heart palpitations and shortness of breath easily. Mental confusion is a huge symptom for me. I have begun taking B12 injections one time per week. I'm on my third day with it, and I am beginning to see a slight improvement. Thank goodness!

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