Despite serious safety concerns, periwinkle is used for "brain health" (increasing blood circulation in the brain, supporting brain metabolism, increasing mental productivity, preventing memory and concentration problems and feebleness, improving memory and thinking ability, and preventing early aging of brain cells).
Periwinkle is also used for treating diarrhea, vaginal discharge, throat ailments, tonsillitis, chest pain, high blood pressure, sore throat, intestinal pain and swelling (inflammation), toothache, and water retention (edema). It is also used for promoting wound healing, improving the way the immune system defends the body, and for "blood-purification."
A chemical in periwinkle called vincamine can be converted in the laboratory to the compound vinpocetine, which is marketed as a dietary supplement.
Insufficient Evidence to Rate Effectiveness for...
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.