blood pressure. It can also help reduce swelling (inflammation) and have a drying (astringent) effect on the tissues.
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nausea, vomiting, and other stomach and intestinal symptoms. It can also cause nerve, kidney, and liver damage. Large amounts can cause very low blood pressure.
Special Precautions & Warnings:Periwinkle is UNSAFE for anyone to use, but people with certain conditions are especially at risk for harmful side effects.
Pregnancy and breast-feeding: Periwinkle is UNSAFE. Don't use it.
Constipation: Periwinkle has a drying effect on tissues. This means it can make constipation worse. Don't use it.
Low blood pressure: Periwinkle can lower blood pressure. If you already have low blood pressure, using periwinkle can make it drop too low. Don't use it.
Surgery: Periwinkle can lower blood pressure. There is a concern that it might interfere with blood pressure control during and after surgery. Stop using periwinkle at least 2 weeks before a scheduled surgery.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.