pergolide - oral, Permax (cont.)
HOW TO USE: Take this medication by mouth with or without food, usually 3 times a day or as directed by your doctor. Taking this medication with food may reduce nausea. To decrease the risk of side effects (e.g., drowsiness, low blood pressure) when you first start taking pergolide, your doctor will slowly increase your dosage until the best dose for you is reached. Take this medication exactly as prescribed. Do not increase your dose or take it more often than directed.Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same times each day. If you are taking levodopa or a carbidopa/levodopa combination, your doctor may direct you to decrease your levodopa dose after you start taking pergolide. Follow your doctor's directions carefully.Do not stop taking this medication without your doctor's approval. If you suddenly stop taking this drug, withdrawal reactions may occur. Such reactions can include fever, muscle stiffness, confusion, and hallucinations. Report any such reactions to your doctor immediately. When stopping extended, regular treatment with this drug, gradually reducing the dosage as directed will help prevent withdrawal reactions. Consult your doctor or pharmacist for more details.The dosage is based on your medical condition and response to treatment. It may take a few weeks for you to notice the full effects of this medication.Tell your doctor if your symptoms do not improve or if they worsen.
SIDE EFFECTS: Nausea, dizziness, drowsiness, trouble sleeping, diarrhea, heartburn, runny nose, constipation, headache, or dry mouth may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: fainting, mental/mood changes (e.g., confusion, depression, hallucinations, memory problems), increased difficulty moving/walking, muscle cramps/spasm, restlessness, decreased sexual function.Some people taking pergolide have reported falling asleep suddenly during their usual daily activities (e.g., watching television, driving). In some cases, sleep occurred without any feelings of drowsiness beforehand. This sleep effect may occur any time during treatment with pergolide, including up to 1 year after starting the medication. Therefore, you should not drive or take part in other possibly dangerous activities until you are certain that this medication will not cause drowsiness or sudden sleep. If you experience increased sleepiness or fall asleep during the day, do not drive or take part in other possibly dangerous activities until you have discussed this effect with your doctor. Your risk is increased with use of alcohol or other medications that can make you drowsy.You may also develop a sudden drop in blood pressure, which can cause dizziness, nausea, sweating, and fainting. This is more likely when you are first starting the medication, when your dose is increased, or when you get up suddenly. To lower your risk, get up slowly from a sitting or lying position.In rare cases, this medication may cause very serious heart valve problems or swelling around the heart and lungs (e.g., pleural fibrosis/effusion, pericarditis). Tell your doctor immediately if you develop any of the following symptoms: difficult/painful breathing, chest pain, unusually slow/fast/irregular heartbeat, swelling of the ankles/feet, unusual weakness.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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