perflutren lipid microsphere suspension-injectable, Definity (cont.)

SIDE EFFECTS: Headache, nausea, or flushing may occur. If any of these effects persist or worsen, notify your doctor. Tell your doctor immediately if any of these serious side effects occurs: back pain, redness/swelling/irritation at the injection site, chest pain. Tell your doctor immediately if any of these unlikely but serious side effects occur: irregular heartbeat, fever, joint pain, tingling or numbness of the hands/feet, stomach pain, vomiting, vision or hearing problems, bruising. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, dizziness, swelling, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor your medical history, especially of: other heart problems (e.g., childhood/congenital defects, pulmonary hypertension), previous heart procedures (e.g., cardiac shunt placement), lung problems (e.g., COPD or emphysema), any allergies (especially to fluorocarbons propellants). Tell your doctor if you are pregnant before using this medication. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription medication you may use. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

NOTES: Laboratory and/or medical tests may be performed to monitor your progress.

MISSED DOSE: Not applicable.

STORAGE: Before mixing, store in the refrigerator between 36 and 46 degrees F (2 and 8 degrees C). Once mixed, the suspension is good for 12 hours at room temperature and stored in the original vial. Discard any unused portion of the vial.

Last Editorial Review: 3/2/2005

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