pentostatin - injection, Nipent

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GENERIC NAME: PENTOSTATIN - INJECTION (PEN-toe-STAT-in)

BRAND NAME(S): Nipent

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: Pentostatin is used to treat a certain type of cancer (hairy cell leukemia). It works by slowing or stopping the growth of cancer cells.OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This drug may also be used to treat other types of cancer (e.g., chronic lymphocytic leukemia).

HOW TO USE: This medication is given by injection into a vein by a health care professional, usually every other week or as directed by your doctor. Dosage is based on your medical condition, body size, and response to treatment.To help reduce side effects to the kidneys, your doctor may prescribe IV fluids before and after you receive pentostatin.

SIDE EFFECTS: Mild rash/itching may occur. Tell your doctor or pharmacist promptly if any of these effects occur. Nausea, vomiting, diarrhea, loss of appetite, increased sweating, or mouth sores may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Many people using this medication have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.Tell your doctor right away if you have any serious side effects, including: change in the amount of urine, dark urine, yellowing eyes/skin, severe stomach/abdominal pain, dizziness, drowsiness, headache, trouble sleeping, shortness of breath, cough, unusual weakness/tiredness, swelling ankles/feet, muscle/joint pain, muscle spasm, mental/mood changes (e.g., depression, anxiety), numbness/tingling of the skin, decreased sexual ability/interest, fainting, fast/slow/irregular heartbeat, vision/hearing changes, pain/redness/swelling of arms or legs.Get medical help right away if any of these rare but very serious side effects occur: seizures, chest pain.This medication may cause very serious blood disorders (decreased bone marrow function leading to low number of blood cells such as red cells, white cells, and platelets). This effect can cause anemia, decrease your body's ability to fight an infection, or cause your body to bruise or bleed more easily. Tell your doctor immediately if you develop any of the following symptoms: signs of infection (e.g., fever, persistent sore throat), easy bruising/bleeding, unusual tiredness, fast/pounding heartbeat.A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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