pentosan, Elmiron (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

DRUG INTERACTIONS: Pentosan resembles heparin and it affects the ability of blood to clot. Therefore, it can cause bleeding and if combined with other drugs that also cause bleeding (anticoagulants) the risk of bleeding may increase. Examples of drugs that cause bleeding include heparin, streptokinase, aspirin, nonsteroidal anti-inflammatory drugs (for example, ibuprofen), and warfarin (Coumadin).

PREGNANCY: Studies with pentosan have not been conducted in pregnant women.

NURSING MOTHERS: Studies of pentosan have not been conducted in nursing mothers.

SIDE EFFECTS: The most common side effects of pentosan are stomach upset, diarrhea, nausea, headache, rash, abdominal pain, hair loss and dizziness. Some patients may develop abnormalities of liver tests in the blood. Bleeding from the rectum and other areas also may occur.

Reference: FDA Prescribing Information

Last Editorial Review: 3/21/2013

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