pentosan, Elmiron

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GENERIC NAME: pentosan


DRUG CLASS AND MECHANISM: Pentosan is a semi-synthetic (man-made) drug that resembles the anticoagulant ("blood thinner") heparin and is used for treating the symptoms of interstitial cystitis. Interstitial cystitis is a condition, usually of unknown cause, in which there is inflammation of the urinary bladder that most frequently causes pelvic pain and frequent urination. The exact mechanism whereby pentosan reduces the symptoms of interstitial cystitis also is unknown; however, scientists believe that pentosan may coat the lining of the bladder and prevent irritating substances in the urine from reaching the cells of the lining. The FDA approved pentosan in September 1996.



PREPARATIONS: Capsules: 100 mg.

STORAGE: Pentosan should be stored at room temperature, between 15 C to 30 C (59 F to 86 F).

PRESCRIBED FOR: Pentosan is used for relieving bladder pain caused by interstitial cystitis.

DOSING: The recommended dose of pentosan is 100 mg three times daily (every 8 hours) taken at least one hour before or two hours after meals so that food does not retard its absorption. Patients should be evaluated after 3 months, and treatment may be continued for another three months if patients have not improved and they are tolerating pentosan.

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