penicillin V potassium (Beepen-VK, Penicillin VK, V-Cillin-K, Veetids)

  • Medical Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

19 Habits That Wreck Your Teeth

Rare (occurring at frequency of <1%) but serious side effects include:

  • acute kidney damage,
  • seizures,
  • severe skin rashes, and
  • hemolytic anemia.

Hypersensitivity reactions have been reported with penicillin use.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Powder for oral solution: 125 mg/5 ml (100 ml, 200 ml); 250 mg/5 ml (100 ml, 200 ml); Tablets: 250 mg, 500 mg

STORAGE: Reconstituted product may be stored for up to 14 days and requires refrigeration 2.2 C to 7.7 C (36 F to 46 F). Un-reconstituted product and oral tablets may be stored at room temperature between 20 C to 25 C (68 F to 77 F).

DOSING: The usual recommended dosage for adults and children 12 years and older are as follows:

Streptococcal infections: For the treatment of mild to moderately severe bacterial infections of the upper respiratory tract, scarlet fever, and cellulitis of the skin (erysipelas): 125 to 250 mg (200,000 to 400,000 unit) every 6 to 8 hours for 10 days.

Pneumococcal infections: For the treatment of mild to moderately severe bacterial infections of the respiratory tract, including otitis media (middle ear infection): 250 to 500 mg (400,000 to 800,000 units) every 6 hours until the patient has been without fever (afebrile) for at least 2 days.

Staphylococcal infections: For the treatment of mild infections of the skin and soft tissue: 250 to 500 mg (400,000 to 800,000 units) every 6 to 8 hours.

Fusospirochetosis (Vincent's infection) of the oropharynx (the part of the throat at the back of the mouth): For the treatment of mild to moderately severe bacterial infections: 250 to 500 mg (400,000 to 800,000 units) every 6 to 8 hours.

Rheumatic fever prophylaxis: 125 to 250 mg (200,000 to 400,000 units) twice daily as maintenance.

Prophylaxis against bacterial endocarditis in patients with congenital heart disease or rheumatic or other acquired heart valve disease who are undergoing dental or surgical procedures involving the upper respiratory tract: Administer 2 grams of penicillin V potassium (1 gram for children weighing < 60 pounds) 1 hour before the procedure, followed by 1 gram (500 mg for children weighing < 60 pounds) 6 hours later.

Medically Reviewed by a Doctor on 12/3/2014
FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

RxList Logo

Need help identifying pills and medications?

Use the pill identifier tool on RxList.

Subscribe to MedicineNet's Newsletters

Get the latest health and medical information delivered direct to your inbox!

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Health Solutions From Our Sponsors