WARNING: This medication must not be injected into a vein or mixed with solutions that will be injected into a vein.
USES: This medication is used to treat a wide variety of bacterial infections. This medication is known as a long-acting natural penicillin antibiotic. It works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.This medication should not be used to treat sexually transmitted diseases (e.g., syphilis, gonorrhea).
HOW TO USE: See also Warning section.This medication is given by injection into a large muscle by a health care professional. The injection should be given slowly and steadily. Do not inject into or near an artery or nerve. Follow all instructions for preparation and use of this product. Before using, check this product visually for unusual particles or discoloration. If either is present, do not use the liquid. If you have questions about the use of this medication, consult the pharmacist.The dosage is based on your medical condition and response to treatment. For children, the dosage is also based on weight.Before injecting each dose, clean the injection site with rubbing alcohol. If you receive more than one dose, it is important to change the location of the injection site to avoid problem areas in the muscle.Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, if more than one dose is needed, use this drug at evenly spaced intervals as prescribed by your doctor, and make sure not to miss any doses.Continue to use this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.Tell your doctor if your condition persists or worsens.
SIDE EFFECTS: Pain at the injection site, nausea, or vomiting may occur. If these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: severe pain/peeling skin at injection site, joint/muscle pain, headache, shortness of breath, dizziness.Tell your doctor immediately if any of these rare but very serious side effects occur: vision changes, fast/slow/pounding heartbeat, numbness/tingling of arms/legs, pain/redness/swelling of arms/legs, change in skin color near injection site or on arms/legs, uncontrolled movements, inability to move, change in the amount of urine, new signs of infection (e.g., fever, persistent sore throat), easy bruising/bleeding, extreme tiredness, dark/cloudy urine, seizures, mental/mood changes (e.g., depression, agitation).Seek immediate medical attention if any of these rare but very serious side effects occur: trouble breathing, chest pain, slurred speech, confusion, fainting.This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have any of the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Clostridium difficile (C. difficile) is a bacterium, and is one of the most common causes of infection of the colon. C. difficile spores are found frequently in hospitals, nursing homes, extended care facilities, and nurseries for newborn infants. They can be found on bedpans, furniture, toilet seats, linens, telephones, stethoscopes, fingernails, rings, floors, infants' rooms, and diaper pails. They even can be carried by pets. Antibiotic-associated (C. difficile) colitis is an infection of the colon caused by C. difficile that occurs primarily among individuals who have been using antibiotics. Treatment for C. difficile colitis hydration, replenishment of electrolyte deficiencies, discontinuing the antibiotic that caused the colitis, and using antibiotics to eradicate the C. difficile bacterium.
Vancomycin-resistant enterococci (VRE) infection is the most common type of infection acquired by patients while hospitalized. Patients at risk for VRE are those who are already ill, and hospitalized, including individuals with diabetes, elderly, ICU patients, kidney failure patients, or patients requiring catheters. Enterococci can survive for months in the digestive tract and female genital tract. Other risk factors for acquiring VRE include those how have been previously treated with vancomycin and combinations of other antibiotics. Treatment of VRE is generally with other antibiotics other than vancomycin. Prevention of VRE can be achieved by proper hand hygiene.
Drug resistance (antimicrobial resistance) is the ability of bacteria, fungi, parasites, and viruses to grow, even in the presence of a drug that would normally kill it (or limit it's growth). Drug resistance is a growing problem, particularly for infections such as MRSA, VRE (vancomycin-resistant enterococci), tuberculosis, HIV, STDs, gonorrhea, flu, pneumonia, malaria, E. coli, salmonella, Campylobacter, which causes diarrhea and gastroenteritis. Learn how to protect yourself from resistance to drugs.
Increasing use of antimicrobials in humans, animals,
and agriculture has resulted in many microbes developing resistance to these
powerful drugs.
Many infectious diseases are increasingly difficult
to treat because of antimicrobial-resistant organisms, including HIV infection, staphylococcal
infection, tuberculosis, influenza, gonorrhea, candida infection, and malaria.
Between 5 and 10 percent of all hospital patients
develop an infection, leading to an increase of about $5 billion in annual
U.S. healthcare costs.
About 90,000 of these patients die each year as a
result of their infection, up from 13,300 patient deaths in 1992.
People infected with antimicrobial-resistant organisms are more likely
to have longer hospital stays and may require more complicated treatment.
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