- What is peginterferon beta-1a plegridy, and how does it work (mechanism of action)?
- What brand names are available for peginterferon beta-1a plegridy?
- Is peginterferon beta-1a plegridy available as a generic drug?
- Do I need a prescription for peginterferon beta-1a plegridy?
- What are the side effects of peginterferon beta-1a plegridy?
- What is the dosage for peginterferon beta-1a plegridy?
- Which drugs or supplements interact with peginterferon beta-1a plegridy?
- Is peginterferon beta-1a plegridy safe to take if I'm pregnant or breastfeeding?
- What else should I know about peginterferon beta-1a plegridy?
What is peginterferon beta-1a plegridy, and how does it work (mechanism of action)?
Peginterferon beta-1a (Plegridy) is a protein produced by recombinant DNA technology using genetically engineered Chinese Hamster Ovary Cells into which the human interferon beta genes have been introduced. It is used for treating multiple sclerosis (MS). It differs from interferon beta-1a by having polyethylene glycol attached to the interferon molecules (peglated) that allow the interferon to remain in the body for longer times thus allowing less frequent dosing. Interferon beta-1a is designed to be identical to interferon beta that is naturally produced by various cells in the body. Interferon beta has antiviral properties and plays a role in regulating the immune response. The exact mechanism by which interferon beta-1a works in the body to treat MS is not known. Interferon beta-1a does not cure MS. Rather it helps to decrease the number of flare-ups and slows the occurrence of some of the physical disability that commonly occurs in the disease. Plegridy works in the same way and has similar side effects as other interferon beta-1a products such as Avonex and Rebif. However, it is given every 14 days versus once weekly or 3 times per week injections. The FDA approved Plegridy in August, 2014.
What brand names are available for peginterferon beta-1a plegridy?
Is peginterferon beta-1a plegridy available as a generic drug?
GENERIC AVAILABLE: No
Do I need a prescription for peginterferon beta-1a plegridy?
What are the side effects of peginterferon beta-1a plegridy?
The most common side effects of interferon beta-1a are:
- injection site reactions,
- flu-like symptoms,
- muscle aches,
- diarrhea, and
Flu-like symptoms are commonly experienced when patients first start taking interferon beta-1a. These symptoms can be managed with over-the-counter pain and fever reducers, and usually decrease or go away over time.
Quick GuideMultiple Sclerosis (MS) Symptoms and Treatment
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Use the pill identifier tool on RxList.