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peginterferon alfa 2b - injection, Pegintron (cont.)

USES: Peginterferon alfa-2b is used alone or in combination with ribavirin to treat chronic hepatitis C, a viral infection of the liver.This medication reduces the amount of hepatitis C virus in the body and helps the body's immune system fight the infection. It is not known if peginterferon can cure hepatitis C virus infections (permanently eliminate the virus from your body). It is also not known if this drug can prevent you from passing the virus to others. Practice "safe sex" (including the use of latex condoms) to lower the risk of passing the virus to others.

HOW TO USE: Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start using peginterferon alfa-2b and each time you get a refill. If you have any questions regarding the information, consult your doctor or pharmacist.Inject this medication under the skin (subcutaneously) on your thigh, the outer surface of your upper arm, or stomach once weekly or as directed by your doctor. Do not inject near the belly button or at the waistline. Use a different place each time you give yourself an injection. The dose should be given at about the same time on the same day each week. The dosage is based on your body weight, medical condition and response to therapy.Drink plenty of fluids while you are taking this medication, unless your doctor directs you otherwise. Additional administration guidelines may be available in the Medication Guide.Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Do not shake this medication. Doing so may decrease the effectiveness of this medication.Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.

SIDE EFFECTS: Flu-like symptoms (e.g., fever, chills, muscle aches, fatigue, headache, joint pain, nausea, stomach pain) may occur. If instructed to do so, taking pain/fever-reducing medications (e.g., acetaminophen, ibuprofen) or injecting this medication at bedtime may help reduce some of these symptoms. Dry mouth, increased sweating, loss of appetite, weight loss, trouble sleeping, diarrhea, dry skin, redness/swelling at the injection site, throat/sinus infections, or menstrual period problems may also occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Temporary hair loss may occur. Normal hair growth should return after treatment has ended.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: persistent sore throat or fever, easy or unusual bleeding/bruising, unusually severe fatigue, increased thirst/urination.Tell your doctor immediately if any of these rare but very serious side effects occur: unusually slow/fast/pounding heartbeat, severe stomach pain with nausea/vomiting, bloody diarrhea, numbness/tingling of arms/legs.Seek immediate medical attention if any of these rare but very serious side effects occur: chest pain, vision changes, seizures, one-sided weakness.This drug may infrequently cause severe mental/mood changes (e.g., suicidal thoughts or severe depression). If you notice these symptoms, stop your treatment with peginterferon and seek immediate medical attention.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.



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