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February 10, 2012
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pegfilgrastim - injection, Neulasta

GENERIC NAME: PEGFILGRASTIM - INJECTION (peg-fill-GRASS-tim)

BRAND NAME(S): Neulasta

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: Pegfilgrastim is a long-acting form of the drug, filgrastim. These drugs, called colony-stimulating factors, are used to help stimulate the bone marrow to make white blood cells in patients who are not able to produce enough white blood cells on their own.White blood cells help the body fight infections. Certain medical conditions (e.g., cancer) and/or medications (e.g., cancer chemotherapy) may reduce the body's ability to make normal white blood cells.

HOW TO USE: Read the Patient Information Leaflet provided by your pharmacist before you start using pegfilgrastim and each time you get a refill. If you have any questions regarding the information, consult your doctor or pharmacist.Avoid shaking this medication; doing so may make the drug ineffective.Remove the medication from the refrigerator 30 minutes before you inject it to allow it to reach room temperature.Inject this medication under the skin (subcutaneously) usually once during each chemotherapy cycle, or as directed by your doctor. The dosage is usually one 6 milligram injection, but it may be adjusted for children or small adults (weighing less than 100 pounds or 45 kilograms).Do not give this drug during the period 14 days before to 1 day after your chemotherapy. Giving this drug during this time may increase your risk of certain side effects. Consult your doctor for details.If you are giving yourself this injection at home, make sure you learn how to prepare and inject this medication properly. Ask your doctor, pharmacist or nurse any questions you may have about how to give yourself pegfilgrastim. Learn how to properly dispose of used syringes, needles, and any unused medication. Never reuse needles or syringes.Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid.Choose a new injection site each time you give yourself a dose. This will help prevent soreness. Never inject pegfilgrastim into skin that is tender, red, bruised, and hard, or has scars or stretch marks.

SIDE EFFECTS: Bone pain may occur. Taking a non-aspirin pain reliever such as acetaminophen may help with this pain. Ask your doctor or pharmacist for more details. Injection site reactions such as redness, swelling, itching, lumps, or bruising may also occur. If any of these effects persist or worsen, notify your doctor promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Seek immediate medical attention if any of these rare but very serious side effects occur: breathing problems (e.g., trouble breathing, shortness of breath, fast breathing).Rarely, possibly fatal damage to the spleen may occur. Seek immediate medical attention if you experience the following side effects: stomach/abdominal pain and/or shoulder pain.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, fast heartbeat, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.




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