paricalcitol - injection, Zemplar (cont.)
PRECAUTIONS: Before using paricalcitol, tell your doctor or pharmacist if you are allergic to it; or to other vitamin D products; or if you have any other allergies.This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: high levels of calcium (hypercalcemia), high levels of vitamin D (hypervitaminosis D).Before using this medication, tell your doctor or pharmacist your medical history, especially of: regular use/abuse of alcohol, brain problems (e.g., seizures, brain injury), heart problems (e.g., arrhythmias, coronary artery disease), liver disease.This medication contains alcohol, which may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is not known whether paricalcitol passes into breast milk. Breast-feeding is not recommended while using this drug. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: other products that contain vitamin D or phosphate (e.g., ergocalciferol, sodium phosphate).If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting paricalcitol.Tell your doctor of all prescription and nonprescription medication you may use, especially: products that contain aluminum/magnesium (e.g., certain antacids, phosphate binders), corticosteroids (e.g., prednisone), digoxin, calcium supplements, drugs affecting liver enzymes that remove paricalcitol from your body (e.g., nefazodone, telithromycin, azole antifungals such as itraconazole/ketoconazole/voriconazole, macrolide antibiotics such as clarithromycin, protease inhibitors such as atazanavir/indinavir/nelfinavir/ritonavir/saquinavir), thiazide diuretics (e.g., hydrochlorothiazide).Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone). Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.Check the labels on all your prescription and nonprescription/herbal products (e.g., antacids, vitamins) because they may contain calcium, phosphate, or vitamin D. Ask your pharmacist about using those products safely.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
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