fats. That's why it works as a meat tenderizer. However, papain is changed by digestive juices, so there is some question about whether it could be effective as a medicine when taken by mouth.
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Papaya also contains a chemical called carpain. Carpain seems to be able to kill certain parasites, and it might affect the central nervous system.
Papaya is POSSIBLY SAFE when taken by mouth as medicine.
Papaya is POSSIBLY UNSAFE when taken by mouth in large amounts or when applied to the skin as papaya latex. Taking large amounts of papaya by mouth could damage the esophagus, which is the food tube in the throat. Applying papaya latex to the skin can cause severe irritation and allergic reactions in some people.
Special Precautions & Warnings:Pregnancy and breast-feeding: Papaya is POSSIBLY UNSAFE when taken by mouth during pregnancy. Do not take papaya by mouth in medicinal amounts if you are pregnant. There is some evidence that unprocessed papain, one of the chemicals found in papaya, might poison the fetus or cause birth defects. Not enough is known about the safety of papaya during breast-feeding. It is best to avoid taking it in amounts higher than normal food amounts.
Diabetes: Papaya that has been fermented can lower blood sugar. People with diabetes who are taking medications to lower their blood sugar should pay close attention to their blood sugar as adjustments to medications might be needed.
Low blood sugar: Papaya that has been fermented can lower blood sugar. Taking this form of papaya might make blood sugar too low in people who already have low blood sugar.
Papain allergy: Papaya contains papain. If you are allergic to papain, avoid eating papaya or taking products that contain papaya.
Latex allergy: If you are allergic to latex, there is a good chance you are also be allergic to papaya. If you have a latex allergy, avoid eating papaya or taking products that contain papaya.
Surgery: Papaya that has been fermented can lower blood sugar. In theory, this form of papaya might affect blood sugary during and after surgery. If you are taking papaya, you should stop 2 weeks before surgery.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.