How does Papain work?

Papain contains substances called enzymes that help break down proteins.

Are there safety concerns?

Papain seems safe for most adults to use as a medicine. It can cause irritation of the throat and stomach. Skin contact with raw papain can cause irritation and blisters.

Excessive amounts of papain can cause severe throat damage.

Do not use papain if:
  • You are pregnant or breast-feeding.
  • You are allergic to fig or kiwi fruit.
  • You have a bleeding disorder.

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Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.