pantoprazole, Protonix (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

SIDE EFFECTS: Pantoprazole like other PPIs is well-tolerated. The most common side effects are:

Rare side effects include:

High doses and long-term use (1 year or longer) of pantoprazole may increase the risk of osteoporosis-related fractures of the hip, wrist, or spine. Therefore, it is important to use the lowest doses and shortest duration of treatment necessary for the condition being treated.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Tablets (Delayed Release): 20, 40 mg. Suspension: 40 mg. Injection: 40 mg

STORAGE: Store at room temperature, 15 C to 30 C (59 F to 86 F). Keep away from moisture.

DOSING:

  • For the treatment for GERD and healing erosive esophagitis the recommended dose for adults is 40 mg daily for 4-8 weeks.
  • The dose for treating Zollinger-Ellison syndrome is 40 mg twice daily.
  • It generally is recommended that tablets be taken approximately 30 minutes prior to meals for maximal effectiveness. Tablets should be swallowed whole and should not be crushed, split or chewed.

DRUG INTERACTIONS: Pantoprazole is less likely than omeprazole to interact with other drugs.

The absorption of certain drugs may be affected by stomach acidity, and, as a result, pantoprazole and other PPIs that reduce stomach acid also reduce the absorption and concentration in blood of ketoconazole (Nizoral) and increase the absorption and concentration in blood of digoxin (Lanoxin). This may lead to reduced effectiveness of ketoconazole or increased digoxin toxicity, respectively.

Medically Reviewed by a Doctor on 12/18/2014


Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.


Back to Medications Index