PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections)

  • Medical Author:
    David Perlstein, MD, MBA, FAAP

    Dr. Perlstein received his Medical Degree from the University of Cincinnati and then completed his internship and residency in pediatrics at The New York Hospital, Cornell medical Center in New York City. After serving an additional year as Chief Pediatric Resident, he worked as a private practitioner and then was appointed Director of Ambulatory Pediatrics at St. Barnabas Hospital in the Bronx.

  • Medical Editor: Roxanne Dryden-Edwards, MD
    Roxanne Dryden-Edwards, MD

    Roxanne Dryden-Edwards, MD

    Dr. Roxanne Dryden-Edwards is an adult, child, and adolescent psychiatrist. She is a former Chair of the Committee on Developmental Disabilities for the American Psychiatric Association, Assistant Professor of Psychiatry at Johns Hopkins Hospital in Baltimore, Maryland, and Medical Director of the National Center for Children and Families in Bethesda, Maryland.

Just a Sore Throat or Strep Slideshow

Can PANDAS be prevented?

For those children diagnosed with PANDAS, there is some evidence that prophylactic antibiotics may play a role in preventing the development of strep infections and therefore the worsening of symptoms. More studies need to be performed to be sure that the preventive treatment is truly effective. Surgical removal of the tonsils and adenoids has not shown to be effective in preventing PANDAS.

Medically reviewed by Robert Cox, MD; American Board of Internal Medicine with subspecialty in Infectious Disease


Singer, H., et al. "Moving from PANDAS to CANS." Journal of Pediatrics 160.5 May 2012: 725-731.

Swedo, S.E., et al. "From research subgroup to clinical syndrome: Modifying the PANDAS criteria to describe PANS." Pediatric & Therapeutics 2.2 (2012).

Medically Reviewed by a Doctor on 2/19/2015

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