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February 10, 2012

Pancreatic Cysts (cont.)

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What are the symptoms of pancreatic cysts?

The symptoms of pancreatic cysts depend on their size and location. Small (less than two cm) cysts usually cause no symptoms. Large pancreatic cysts can cause abdominal pain and back pain presumably by putting pressure on surrounding tissues and nerves. Large cysts in the head of the pancreas also may cause jaundice (yellowing of the skin and eyes with darkening of urine color) due to obstruction of the common duct. Obstruction causes bile to back up and forces bilirubin (the chemical that produces jaundice) back into the bloodstream.

On rare occasions, acute pancreatitis can cause the formation of large pseudocysts that can compress the stomach or the duodenum leading to obstruction to flow within the intestines, abdominal pain and vomiting. These cysts also may become infected and lead to fever, chills, and sepsis.

What are the different causes and types of pancreatic cysts?

There are two major types of pancreatic cysts; inflammatory cysts and noninflammatory cysts. Inflammatory cysts are benign, whereas noninflammatory cysts can be benign, precancerous, or cancerous.

Inflammatory cysts

Most of the inflammatory cysts of the pancreas are pancreatic pseudocysts. Pseudocysts of the pancreas result from pancreatitis (inflammation of the pancreas). The common causes of pancreatitis include alcoholism, gallstones, trauma, or surgery. The fluid inside the pseudocysts represents liquefied dead pancreatic tissue, cells of inflammation, and a high concentration of digestive enzymes (for example, amylase). Most pseudocysts caused by acute pancreatitis resolve spontaneously (without treatment) within several weeks. Pseudocysts that need treatment are those that persist beyond six weeks and are causing symptoms such as pain, obstruction of the stomach or duodenum, or become infected.


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