Pancreas Divisum

  • Medical Author:
    David Perlstein, MD, MBA, FAAP

    Dr. Perlstein received his Medical Degree from the University of Cincinnati and then completed his internship and residency in pediatrics at The New York Hospital, Cornell medical Center in New York City. After serving an additional year as Chief Pediatric Resident, he worked as a private practitioner and then was appointed Director of Ambulatory Pediatrics at St. Barnabas Hospital in the Bronx.

  • Medical Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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How is pancreas divisum diagnosed?

The most accurate test to diagnose pancreas divisum is ERCP (endoscopic retrograde cholangio-pancreatography), which can demonstrate the presence of two separately draining pancreatic ducts. However, ERCP itself sometimes can cause attacks of pancreatitis. Other tests that can help diagnose pancreas divisum without the risk of causing pancreatitis include endoscopic ultrasound (EUS), and MRI (magnetic resonance imaging).

What is the treatment for pancreas divisum?

Pancreas divisum without symptoms needs no treatment. Treatment of patients with abdominal pain and recurrent pancreatitis attributable to pancreas divisum has not been well established. Some doctors will attempt sphincterotomy (cutting of the minor papilla during ERCP to enlarge its opening). Others will insert a stent during ERCP into the duct to prevent duct blockage. These procedures are not risk free. Therefore, patients with symptomatic pancreas divisum are best evaluated and treated by doctors in centers experienced in treating pancreatic diseases.

What is the prognosis for pancreas divisum?

Most patients with pancreas divisum remain asymptomatic and therefore the prognosis is excellent. For those patients with symptoms of pancreatitis, the prognosis is no different than that of the unaffected population who develop pancreatitis. Even after treatment, pancreatitis may recur. It is important to remember that there is no clear evidence to support a causal relationship between pancreas divisum and pancreatitis.

Medically reviewed by John A. Daller, MD; American Board of Surgery

REFERENCE: MedscapeReference.com. Pancreas Divisum.

Previous contributing author: Dennis Lee, MD.

Medically Reviewed by a Doctor on 3/18/2016

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