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February 9, 2012

Pancreas Divisum

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What is pancreas divisum?

Pancreas divisum is a common congenital anomaly (an anomaly that is present at birth) of the pancreatic duct(s). The Pancreas is a deep-seated organ located behind the stomach. One of its functions is to produce enzymes that are important for the digestion of food in the intestine. The digestive enzymes, in the form of digestive juice, drain from the pancreas via the pancreatic duct into the duodenum (the upper portion of the small intestine) where they aid in digesting food.

What causes pancreas divisum?

The human embryo starts life with two ducts in the pancreas; the ventral duct and the dorsal duct. In more than 90% of the embryos, the dorsal and the ventral ducts will fuse to form one main pancreatic duct. The main pancreatic duct will join the common bile duct (the duct that drains bile from the gallbladder and the liver) to form a common bile and pancreatic duct which drains into the duodenum through the major papilla. In approximately 10% of embryos, the dorsal and the ventral ducts fail to fuse. Failure of the ventral and the dorsal pancreatic ducts to fuse is called pancreas divisum (because the pancreas is drained by two ducts). In pancreas divisum, the ventral duct drains into the major papilla, while the dorsal duct drains into a separate minor papilla.

What are pancreas divisum symptoms?

The majority of individuals born with pancreas divisum experience no symptoms throughout life, will remain undiagnosed and will not require treatment. A small number of patients with pancreas divisum will experience repeated episodes of pancreatitis. Pancreatitis is an inflammation of the pancreas that can cause severe abdominal pain and more severe complications. Some patients with pancreas divisum may develop chronic abdominal pain without pancreatitis.

Doctors are not certain how pancreas divisum causes abdominal pain and pancreatitis. One theory is that the minor papilla is too narrow to adequately drain the digestive juices in the dorsal duct. The backup of the digestive juices elevates the pressure in the minor duct that causes abdominal pain and pancreatitis.

For more, please read the Pancreatitis and Abdominal Pain articles.




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Pancreas Divisum

Digestion Introduction

"Just a spoonful of sugar... " goes the song. But what happens to that sugar once you swallow it? In fact, how is it that you are able to swallow it at all? Your digestive system performs amazing feats every day, whether you eat a double cheeseburger or a stalk of celery. Read on to learn what exactly happens to food as it makes its way through your digestive system.

What Is Digestion?

Digestion is the complex process of turning the food you eat into the energy you need to survive. The digestion process also involves creating waste to be eliminated.

The digestive tract (or gut) is a long twisting tube that starts at the mouth and ends at the anus. It is made up of a series of muscles that coordinate the movement of food and other cells that produce enzymes and hormones to aid in the breakdown of food. Along the way are three other organs that are needed for digestion: the liver, gallbladder, and the ...

Read the The Digestive System article »




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