GENERIC NAME: PALONOSETRON - INJECTION (pal-oh-NOE-se-tron)

BRAND NAME(S): Aloxi

Medication Uses | Other Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: This medication is used to prevent nausea and vomiting caused by cancer chemotherapy. It works by blocking the hormone (serotonin) that causes vomiting.

OTHER USES: This medication may also be used to prevent nausea and vomiting after surgery.

HOW TO USE: This medicine is injected into a vein (intravenous-IV) as a one-time dose 30 minutes before chemotherapy begins. Repeating a dose within 7 days is not recommended. Consult your doctor or pharmacist for more details. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid.

SIDE EFFECTS: Headache, constipation, diarrhea, or dizziness may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: irregular heartbeat, fainting. A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (e.g., QTc prolongation, arrhythmias), low mineral levels (electrolyte imbalances such as low potassium or magnesium), any allergies (especially to other serotonin receptor blockers such as ondansetron, dolasetron). This drug may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Breast-feeding is not recommended while using this drug.