Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.
Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.
Catherine Burt Driver, MD, is board certified in internal medicine and rheumatology by the American Board of Internal Medicine. Dr. Driver is a member of the American College of Rheumatology. She currently is in active practice in the field of rheumatology in Mission Viejo, Calif., where she is a partner in Mission Internal Medical Group.
The outlook is generally good, particularly if treatment is given before major changes in the affected bones have occurred. Paget's disease occurs most frequently in the spine, skull, pelvis, thighs, and lower legs. In general, symptoms progress slowly. Paget's disease is not a cancer, and the disease does not spread to normal bones. Treatment can control Paget's disease and lessen symptoms, but treatment does not cure Paget's disease.
Who discovered Paget's disease?
Paget's disease is
named after the English surgeon Sir James Paget, who described the condition in
1877. Paget also discovered the worm that causes trichinosis and described what
is called Paget's disease of the breast. Together with Rudolph Virchow in
Germany, Paget was one of the founders of pathology.
Where can I find more information about Paget's disease?
For further information, contact the Paget's
Disease Foundation.
The Paget's Disease Foundation
120 Wall Street, Suite 1602
New York, NY 10005-4001
Phone: 212-509-5335
Fax: 212-509-8492 pagetfdn@aol.com
Paget's disease can cause pain in the
bones or joints, headaches and hearing loss, pressure on nerves, increased head
size, bowing of limb, or curvature of spine.
Tests used to diagnose Paget's
disease include X-rays, blood tests, and bone scanning.
Paget's disease can
lead to other medical conditions.
Medical treatment options include aspirin,
other anti-inflammatory medications, pain medications, and medications that slow
the rate of bone turnover, decreasing the activity of Paget's disease.
Surgical operations may necessary for damaged joints, fractures, severely
deformed bones, or when nerves are being pinched by enlarged bone.
REFERENCES:
Klippel, J.H., et al. Primer on the Rheumatic Diseases. New York: Springer, 2008.
Whyte, Michael P. "Paget's Disease of Bone." New England Journal of Medicine 355 (2006): 593-600.
Congestive heart failure (CHF) is a condition in which the heart's function as a pump is inadequate to meet the body's needs. A poor blood supply resulting from congestive heart failure may cause the body's organ systems to fail, leading to a weakened heart muscle and fluid accumulation in the lungs and body tissue. There are many diseases that can impair pumping efficiency and symptoms of congestive heart failure including fatigue, diminished exercise capacity, shortness of breath, and swelling. Treatments include lifestyle modifications, medications, heart transplant, and therapy.
Headaches can be divided into two categories: primary headaches and secondary headaches. Migraine headaches, tension headaches, and cluster headaches are considered primary headaches. Secondary headaches are caused by disease. Headache symptoms vary with the headache type. Over-the-counter pain relievers provide short-term relief for most headaches.
Arthritis is inflammation of one or more joints. When joints are inflamed they can develop stiffness, warmth, swelling, redness and pain. There are over 100 types of
arthritis including osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, lupus, gout,
and pseudogout.
Fractures occur when bone cannot withstand the outside forces applied to the bone. Fractures can be open or closed. Types of fractures include: greenstick, spiral, comminuted, transverse, compound, or vertebral compression. Common fractures include: stress fracture, compression fracture, rib fracture, and skull fracture. Treatment depends upon the type of fracture.
Cauda equina syndrome is a medical emergency condition that is caused by the uncommon compression of the nerves at the end of the spinal cord. Symptoms of cauda equina syndrome include lower back pain, tingling and/or numbness in the buttocks and lower extremities, bowel or bladder incontinence, and weakness in the legs. Causes of cauda equina syndrome include herniated discs, hematomas, or infection. Treatment is generally prompt surgery.
Blindness is the state of being sightless. Causes of blindness include macular degeneration, stroke, cataract, glaucoma, infection and trauma. Symptoms and signs may include eye pain, eye discharge, or the cornea or pupil turning white. Treatment of blindness depends upon the cause of the blindness.
Hearing loss (deafness) may be present at birth or it may manifest later in life. Deafness may be genetic or due to damage from noise. Treatment of deafness depends upon its cause.
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