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Paget's Disease Center - Erie, PA

Erie Rheumatologist Doctors for Paget's Disease

Type of Physician: Rheumatologist

What is a Rheumatologist?

A subspecialty certification by the Board of Internal Medicine; practitioners treat diseases of the joints, muscles, bones, and tendons. The rheumatologist diagnoses and treats arthritis, back pain, muscle strains, common athletic injuries, etc. The rheumatologist may work closely with other specialists such as orthopaedic surgeons and physical therapists.

Specialty: Rheumatology

Common Name:

Rheumatologist Doctors in Erie *

Arthritis Associates
Kathe S Bryson
3317 Liberty St
Erie, PA 16508
(814) 868-8531

Arthritis Associates
Edward E Engel
3317 Liberty St
Erie, PA 16508
(814) 868-8531

Arthritis Associates
Theresa J Fryer
3317 Liberty St
Erie, PA 16508
(814) 868-8531

Arthritis Associates
Charles G Herbst
3317 Liberty St
Erie, PA 16508
(814) 868-8531

William S Makarowski MD FACR
William S Makarowski
1781 W 26th St
Erie, PA 16508
(814) 454-5896

Northwest Physicians Associates
Gerald E LaRochelle
1012 Water St
Meadville, PA 16335
(814) 337-8532

Magdy K Iskander MD
Magdy K Iskander
745 E State St
Sharon, PA 16146
(724) 983-0800

Mitra Arthritis & Osteoporosis Center PC
Devashis A Mitra
5 Lyn Mar Plaza
Lyndora, PA 16045
(724) 282-5244

Erie, Pennsylvania

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Paget's Disease

What is Paget's disease?

Paget's disease is a chronic bone condition characterized by disorder of the normal bone remodeling process. Normal bone has a synchronized relationship of mechanisms that act to lay down new bone and take up old bone. This relationship (referred to as remodeling) is essential for maintaining the normal calcium levels in our blood. In bone affected by Paget's disease, the bone remodeling is disturbed and not synchronized. As a result, the bone that is formed is abnormal, enlarged, not as dense, brittle, and prone to breakage (fracture).

Paget's disease affects older bone of adults. It's estimated that 1% of adults in the U.S. have Paget's disease. There is an extremely rare form of Paget's disease in children, referred to as juvenile Paget's disease. Paget's disease is also known as osteitis deformans.

What causes Paget's disease?

It is not known what causes Paget's disease. Recently, certain genes have been associated with Paget's disease, including the Sequestrosome 1 gene on chromosome 5. Virus infection may be necessary to trigger Paget's disease in people who have inherited the genetic tendency to develop the condition.

What are symptoms of Paget's disease?

Paget's disease commonly causes no symptoms and is incidentally noted when X-ray tests are obtained for other reasons. However, Paget's disease can cause bone pain, deformity, fracture, and arthritis. The bone pain of Paget's disease is located in the affected bone. The most common bones affected by Paget's disease include the spine, the thigh bone (femur), the pelvis, the skull, the collar bone (clavicle), and the upper arm bone (humerus).

The symptoms of Paget's disease depend on the bones affected and the severity of the disease. Enlarged bones can pinch adjacent nerves, causing tingling and numbness. Bowing of the legs can occur. Hip or knee i...

Recommended Reading Related to Paget's Disease

Arthritis »

What is arthritis? What causes arthritis?

Arthritis is a joint disorder featuring inflammation. A joint is an area of the body where two different bones meet. A joint functions to move the body parts connected by its bones. Arthritis literally means inflammation of one or more joints.

Arthritis is frequently accompanied by joint pain. Joint pain is referred to as arthralgia.

There are many types of arthritis (over 100 identified, and the number is growing). The types range from those related to wear and tear of cartilage (such as osteoarthritis) to those associated with inflammation resulting from an overactive immune system (such as rheumatoid arthritis). Together, the many types of arthritis make up the most common chronic illness in the United States.

The causes of arthritis depend on the form of arthritis. Causes include injury (leading to osteoarthritis), metabolic abnormalities (such as gout and pseudogout), hereditary facto...

Emergency Contact for Erie

  • In case of Emergency, call 911

Nearby Erie Hospitals *

Hamot Medical Center
201 State St
Erie, PA 16550
(814)877-6000

HEALTHSOUTH Rehabilitation Hospital of Erie
143 E 2nd St
Erie, PA 16507
(814)878-1200

Select Specialty Hospital Erie
252 W 11th St
Erie, PA 16501
(814)874-5301

Saint Vincent Health Center
232 W 25th St
Erie, PA 16544
(814)452-5000

Erie VA Medical Center
135 E 38 St
Erie, PA 16504
(814)868-8661

Shriners Hospital for Children Erie
1645 W 8th St
Erie, PA 16505
(814)875-8700

Millcreek Community Hospital
5515 Peach St
Erie, PA 16509
(814)864-4031

Corry Memorial Hospital
612 W Smith St
Corry, PA 16407
(814)664-4641

University Hospitals Conneaut Medical Center
158 W Main Rd
Conneaut, OH 44030
(440)593-1131

Westfield Memorial Hospital
189 E Main St
Westfield, NY 14787
(716)326-4921

Meadville Medical Center
751 Liberty St
Meadville, PA 16335
(814)333-5000

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