oxycodone and acetaminophen, Percocet, Roxicet, Tylox, Endocet (discontinued), Oxycet, (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
Other important side effects include:
Oxycodone can depress breathing and, therefore, is used with caution in elderly, debilitated patients and in patients with serious lung disease. Oxycodone can impair thinking and the physical abilities required for driving or operating machinery. Oxycodone can be habit-forming. Mental and physical dependence can occur but are unlikely when used for short-term pain relief.
GENERIC AVAILABLE: Yes
PREPARATIONS: Tablets: 2.5/325, 5/325, 7.5/500, 10/650 mg (oxycodone/acetaminophen); Capsules: 5/500 mg; Solution: 5/325 mg per teaspoonful.
STORAGE: Oxycodone/acetaminophen should be stored at room temperature in a sealed, light-resistant container.
DOSING: The dose of oxycodone/acetaminophen is variable and depends on the needs of the patient and specific circumstances. The usual dose is one tablet every six hours as needed. The maximum oxycodone/acetaminophen dose is 60 mg/4 g per day.
DRUG INTERACTIONS: Oxycodone, like other narcotic pain-relievers, increases the effect of drugs that slow brain function, such as alcohol, barbiturates, skeletal muscle relaxants, for example, carisoprodol (Soma), cyclobenzaprine (Flexeril), and benzodiazepines such as diazepam (Valium) and lorazepam (Ativan). Combined use of muscle relaxants or benzodiazepines and oxycodone may lead to increased respiratory depression.
Drugs which stimulate and also block opioid receptors, for example, pentazocine, nalbuphine (Nubain), butorphanol (Stadol), and buprenorphine (Subutex) may reduce the effect of oxycodone and may precipitate withdrawal symptoms.
Medically Reviewed by a Doctor on 1/13/2015
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