oxycodone and acetaminophen (Percocet, Roxicet, Tylox, Oxycet)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Surprising Reasons You're in Pain Slideshow

GENERIC NAME: oxycodone and acetaminophen

BRAND NAMES: Percocet, Primlev, Roxicet, Endocet, Xartemis XR

DISCONTINUED BRANDS: Xolox, Tylox, Oxycet, Roxilox

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

USES: Oxycodone/acetaminophen is prescribed for the relief of moderate to moderately-severe pain.

SIDE EFFECTS:

The most frequent adverse reactions of oxycodone/acetaminophen are

Other important side effects include:

  • drowsiness,
  • constipation, and
  • spasm of the ureter, which can lead to difficulty in urinating.

Possible serious side effects include

  • severe reduction in blood pressure (hypotension),
  • shock,
  • seizures,
  • paralytic ileus,
  • serious allergic reactions, and
  • severe skin reactions.

Oxycodone can depress breathing and, therefore, is used with caution in elderly, debilitated patients and in patients with serious lung disease. Oxycodone can impair thinking and the physical abilities required for driving or operating machinery. Oxycodone can be habit-forming. Mental and physical dependence can occur but are unlikely when used for short-term pain relief.

PREPARATIONS:

  • Tablets: 2.5/325, 5/300, 5/325, 7.5/300, 7.5/325, 10/300, 10/325 mg (oxycodone/acetaminophen)
  • Tablets (Extended Release): 4.8/325 mg.
  • Solution: 5/325 mg per teaspoonful
Medically Reviewed by a Doctor on 7/28/2016

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