oxycodone, Oxycontin, Roxicodone, Oxect (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Drugs which stimulate and also block opioid receptors for example, pentazocine, nalbuphine (Nubain), butorphanol (Stadol), and buprenorphine (Subutex) may reduce the effect of oxycodone and may precipitate withdrawal symptoms.

A fatty meal may increase the absorption of oxycodone by 27%.

PREGNANCY: Safety during pregnancy has not been established. Children born to mothers who were taking oxycodone for a prolonged period may exhibit respiratory depression or withdrawal symptoms.

NURSING MOTHERS: Small amounts of oxycodone are secreted in breast milk and may cause side effects in the newborn.

SIDE EFFECTS: The most frequent side effects of oxycodone include lightheadedness, dizziness, sedation, nausea, vomiting, headache, rash, constipation, dry mouth, and sweating.

Oxycodone can depress breathing and is used with caution in elderly, debilitated patients and in patients with serious lung disease. Oxycodone can impair thinking and the physical abilities required for driving or operating machinery. Oxycodone is habit forming. Mental and physical dependence can occur but are unlikely when used for short-term pain relief. If oxycodone is suddenly withdrawn after prolonged use, symptoms of withdrawal may develop. The dose of oxycodone should be gradually reduced in order to avoid withdrawal symptoms.

Reference: FDA Prescribing Information


Medically Reviewed by a Doctor on 7/31/2014


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