GENERIC NAME: oxaprozin
BRAND NAME: Daypro
DRUG CLASS AND MECHANISM: Oxaprozin is a nonsteroidal
anti-inflammatory drug (NSAID) effective in treating fever,
pain, and
inflammation in the body. As a group, NSAIDs are non-narcotic
relievers of
mild to moderate pain of many causes, including injury,
menstrual cramps,
arthritis, and other musculoskeletal conditions. Since the
response to
different NSAIDs varies from patient to patient, it is not
unusual for a
doctor to try different NSAIDs for any given condition.
PRESCRIPTION: yes
GENERIC AVAILABLE: no
PREPARATIONS: tablet: 600mg
STORAGE: Store at room temperature, sealed container,
avoid
moisture.
PRESCRIBED FOR: Oxaprozin is used for the treatment of
inflammation and pain that results from rheumatoid arthritis and
osteoarthritis.
DOSING: Should be taken with food.
DRUG INTERACTIONS: Oxaprozin should be avoided by
patients with
a history of asthma exacerbation, hives, or other allergic
reactions to
aspirin or other NSAIDs. Rare but severe allergic reactions
have been
reported in such individuals. It also should be avoided by
patients with
peptic ulcer disease or poor kidney function, since this
medication can
aggravate both conditions. Oxaprozin is generally used with
caution in
patients taking blood thinning medications (anticoagulants)
such as
warfarin (Coumadin), because of an increased risk of bleeding.
Patients
taking lithium can develop toxic blood lithium levels. Patients
taking
cyclosporine (Sandimmune) can develop kidney toxicity. Use in
children has
not been adequately studied. Oxaprozin is not habit forming.
NSAIDs should
be discontinued prior to elective surgery because of a mild
interference
with clotting that is characteristic of this group of
medicines. Oxaprozin
is best discontinued at least five days in advance of the
procedure.
Persons who have more than 3 alcoholic beverages per day are at
increased risk of developing stomach ulcers when taking
ibuprofen or other
NSAIDs.
PREGNANCY: Oxaprozin is generally avoided during
pregnancy.
NURSING MOTHERS: Oxaprozin is generally avoided in
nursing
mothers.
SIDE EFFECTS: Most patients benefit from oxaprozin and
other
NSAIDs with few side effects. However, serious side effects can
occur, and
generally tend to be dose related. Therefore, it is advisable
to use the
lowest effective dose to minimize side effects. The most common
side
effects of oxaprozin involve the gastrointestinal system. It
can cause
ulcerations, abdominal pain, cramping, nausea, gastritis, and
even serious
gastrointestinal bleeding and liver toxicity. Sometimes,
stomach
ulceration and bleeding can occur without any abdominal pain.
Black tarry
stools, weakness, and dizziness upon
standing may be the only signs of internal bleeding. Rash, kidney impairment, ringing in the
ears, and
lightheadedness can also occur.
Last Editorial Review: 12/31/1997
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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From the Doctors at MedicineNet.com  |
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- Rheumatoid Arthritis - Learn more about rheumatoid arthritis, an autoimmune disease that causes chronic joint inflammation, which has symptoms that include stiffness, fever, muscle and joint aches, loss of appetite, and fatigue. Treatment of rheumatoid arthritis incorporates the use of first-line drugs (aspirin and corticosteroids for pain and inflammation) and second-line drugs (methotrexate and hydroxychloroquine to prevent joint destruction and promote remission). Source:MedicineNet
- Osteoarthritis - Osteoarthritis (degenerative arthritis) is a joint disease caused by the breakdown and loss of the cartilage of one or more joints. With repetitive use, pain, swelling, warmth, and creaking may be noticed in the affected joint. Though weight loss and avoiding stress on the joint will reduce joint pain and inflammation, there is no specific treatment for osteoarthritis. Source:MedicineNet
- Arthritis - Read about arthritis causes, diagnosis, information, symptoms, and treatment. Symptoms of this type of disorder include joint pain, swelling, and inflammation. Source:MedicineNet
- Read 30 more oxaprozin related articles ...
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