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February 9, 2010
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Overactive Bladder

Medical Author: Siamak Nabili, MD, MPT
Medical Editors: Dennis Lee, MD, and William C. Shiel Jr., MD, FACP, FACR

What is an overactive bladder?

An overactive bladder is a condition that results from sudden, involuntary contraction of the muscle in the wall of the urinary bladder. Overactive bladder causes a sudden and unstoppable need to urinate (urinary urgency), even though the bladder may only contain a small amount of urine.

Overactive bladder is also referred to as urge incontinence and is a form of urinary incontinence (unintentional loss of urine). Another common type of urinary incontinence is called stress incontinence, which is caused by anatomic weakness in the structures that prevent the bladder from leaking. In general, urinary incontinence is more common in women compared to men.

Although it can happen at any age, overactive bladder is especially common in older adults. Overactive bladder affects an estimated one in 11 adults in the United States. Overactive bladder, however, should not be considered a normal part of aging.

What are the causes of overactive bladder?

Overactive bladder is typically caused by spasms of the muscles of the bladder, resulting in an urge to urinate (hence, urge incontinence). Overactive bladder is primarily a problem of the nerves and muscles of the bladder. Detrusor is one of the major muscles of the bladder. Its contraction in response to filling of the bladder by urine is one the steps in the normal process of urination. The contraction and relaxation of the detrusor muscle is regulated by the nervous system. Approximately 300 cc of urine in the bladder can signal the nervous to trigger muscles of the bladder to coordinate urination. Voluntary control of the sphincter muscles at the opening of the bladder can hold the urine in the bladder for longer. Up to 600 cc of urine can be contained in a normal adult bladder.

Overactive bladder typically results from inappropriate contraction of the detrusor muscle regardless of the amount of urine.

The common abnormalities of the nervous system that cause of overactive bladder are

There are also some causes of overactive bladder and urge incontinence with a normal nervous system. For example, urinary tract infection, bladder stones, or bladder tumors can cause also cause overactivity of the detrusor muscle, leading to overactive bladder.

Sometimes no apparent cause of overactive bladder can be determined (idiopathic overactive bladder).



Next: Are there any risk factors for overactive bladder? »

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Latest Medical News


ENABLEX is a prescription medicine used in adults to treat the following symptoms due to a condition called overactive bladder:

  • · having a strong need to go to the bathroom right away (also called "urgency")
  • · leaks or wetting accidents (also called "urinary incontinence")
  • · having to go to the bathroom too often (also called "urinary frequency")

IMPORTANT SAFETY INFORMATION

You should not take once-daily ENABLEX if you have certain types of stomach problems, glaucoma, or have trouble emptying your bladder. Side effects of ENABLEX include blurred vision, and more commonly dry mouth, constipation, indigestion, and abdominal pain. Use caution when doing certain activities until you know how ENABLEX affects you.


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Overactive Bladder

How does the urinary system work?

Urination, or voiding, is a complex activity. The bladder is a balloon-like organ that lies in the lowest part of the abdomen. The bladder stores urine, then releases it through the urethra, the canal that carries urine to the outside of the body. Controlling this activity involves nerves, muscles, the spinal cord, and the brain.

The bladder is composed of two types of muscles: the detrusor, a muscular sac that stores urine and squeezes to empty; and the sphincter, a circular group of muscles at the bottom or neck of the bladder that automatically stay contracted to hold the urine in and automatically relax when the detrusor contracts to let the urine into the urethra. A third group of muscles below the bladder (pelvic floor muscles) can contract to keep urine back.

A baby's bladder fills to a set point, then automatically contracts and empties. As the child gets older, the nervous system matures. ...

Read the Urinary Incontinence in Children article »











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