- Surprising Reasons You're in Pain Slideshow
- Take the Pain Quiz
- Joint-Friendly Exercises to Reduce RA Pain Slideshow
- What is orphenadrine-oral, and how does it work (mechanism of action)?
- What brand names are available for orphenadrine-oral?
- Is orphenadrine-oral available as a generic drug?
- Do I need a prescription for orphenadrine-oral?
- What are the side effects of orphenadrine-oral?
- What is the dosage for orphenadrine-oral?
- Which drugs or supplements interact with orphenadrine-oral?
- Is orphenadrine-oral safe to take if I'm pregnant or breastfeeding?
- What else should I know about orphenadrine-oral?
What is orphenadrine-oral, and how does it work (mechanism of action)?
Orphenadrine is an oral central acting skeletal muscle relaxant that is used for the treatment of acute muscle aches, pain, or spasms. The exact mechanism of action in relieving muscuar aches or spasms is not completely understood. Orphenadrine may reduce muscle spasms through actions on motor centers or the medulla in the brain. Orphenadrine does not seem to have any direct relaxant effects on skeletal muscle.
Orphenadrine is structurally related to the antihistamine diphenhydramine (Benadryl), however, its antihistamine activity is less than that of diphenhydramine. Orphenadrine also has some local anesthetic effects. The FDA approved Orphenadrine in 1959.
What brand names are available for orphenadrine-oral?
Norflex (Discontinued in the US)
Is orphenadrine-oral available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for orphenadrine-oral?
What are the side effects of orphenadrine-oral?
Side effects of orphenadrine include:
- increased heart rate,
- urinary retention,
- dry mouth,
- dry eyes,
- upset stomach,
- weakness, and
- nasal congestion.
Quick GuideChronic Pain: Causes and Solutions
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