Optic Neuritis (cont.)

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What is the prognosis for optic neuritis?

The prognosis depends on the underlying cause. Most episodes resolve spontaneously, with return of vision in two weeks to three months. About 90% of people with optic neuritis will recover most of their vision within six months of onset. However, about 14% will have a recurrence of optic neuritis in the affected eye, and 12% will develop optic neuritis in the other eye within 10 years. If the patient has one or more abnormal lesions on the MRI, the risk of MS within 15 years is 72%.

Where can I find more information on optic neuritis?

American Academy of Ophthalmology
http://www.aao.org

Medically reviewed by John P. Keenan, MD; Board Certified Opthamology

REFERENCES:

Beck, R.W., Cleary, P.A., et al. "Optic Neuritis Treatment Trial." Arch Ophthalmol 3 (1993): 773-775.

Beck, R.W., Trobe, J.D. "What we have learned FROM the Optic Neuritis Treatment Trial." Ophthalmology 10 (1995): 1504-1509.

Brewis, M., Poskanzer, D.C., Rolland, C., et al. "Neurological disease in an English city." Acta Neurol Scand 42 (Suppl 24) (1965): 1.

Celesia, G.G., Kaufman, D.I., Brigell, M., et al. "Optic neuritis: A prospective study." Neurology 40 (1990): 919.

Griffin, J.F., Wray, S.H. "Acquired color vision defects in retrobulbar neuritis." Am J Ophthalmol 86 (1978): 193.

Hess, R.F., Plant, G.T. "The psychophysical loss in optic neuritis: spatial and temporal aspects." In Optic Neuritis. Cambridge: Cambridge University Press, 1986, p 109.

Lillie, W.I. "The clinical significance of retrobulbar and optic neuritis." Am J Ophthalmol 17 (1934): 110.

Nikoskelainen, E. "Symptoms, signs and early course of optic neuritis." Acta Ophthalmol 53 (1975): 254.

Percy, A.K., Nobrega, F.T., Kurland, L.T. "Optic neuritis and multiple sclerosis." Arch Ophthalmol 87 (1972):135.

Perkin, G.D., Rose, C.F. Optic Neuritis and its Differential Diagnosis. Oxford: Oxford University Press, 1979, p 206.

Rizzo, J.F., Lessell, S. "Risk of developing multiple sclerosis after uncomplicated optic neuritis: A long term prospective study." Neurology 38 (1988): 185-190.

Sanders, E.A.C.M., Volkers, A.C.W., van der Poel, J.C., et al. "Estimation of visual function after optic neuritis: A comparison of clinical tests." Br J Ophthalmol 70 (1986): 918.

Van Dalen, J.T.W., Greve, E.L. "Visual field defects in multiple sclerosis." Neuro-ophthalmology 2 (1981):93.

Wray, S.H. "Optic Neuritis." Principles and Practice of Ophthalmology, volume 4, 2539-2568.


Medically Reviewed by a Doctor on 1/21/2014

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