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GENERIC NAME: ONDANSETRON - ORAL (on-DANS-eh-tron)

BRAND NAME(S): Zofran

Medication Uses | Other Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert

USES: This medication is used to prevent nausea and vomiting caused by cancer chemotherapy or after surgery. It works by blocking the hormone (serotonin) that causes vomiting.

OTHER USES: This medication may also be used to treat alcoholism.

HOW TO USE: This medication may be taken with or without food. It may also be taken with antacids. The first dose is usually taken 30 minutes before chemotherapy. Take further doses as directed, usually for 1-2 days after completion of chemotherapy. Other medical conditions and procedures require different dosing schedules. Follow your doctor's orders carefully.

SIDE EFFECTS: Diarrhea or constipation, headache, lightheadedness or drowsiness (uncommon), as well as blurred vision may occur. If these effects persist or worsen, notify your doctor promptly. Very unlikely but report promptly: chest pain. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor your medical history, especially of: stomach/intestinal problems (e.g., distension), liver disease, any allergies. Limit alcohol intake, as it may intensify drug side effects. Caution performing tasks requiring alertness (e.g., driving) until you know how this medication affects you. Tell your doctor if you are pregnant before using this medication. It is not known if this drug is excreted into breast milk. Consult your doctor before breast-feeding.




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Suggested Reading by Our Doctors
MedicineNet Doctors
  • Nausea and Vomiting - Nausea and vomiting symptoms of many conditions including motion sickness, pregnancy, emotional stress, gallbladder disease, and more. Learn how to recognize the warning signs of nausea and vomiting on MedicineNet.com
  • Cancer - Learn about cancer types, disease statistics, facts, and survival rates, and get information about how malignant tumors (cancerous growths) metastasize or spread.
  • Antiemetics - Learn some of the causes of nausea and vomiting (pregnancy, motion sickness, overeating, postoperative) and read about treatments and their side effects.

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ondansetron-oral, Zofran

What can cause nausea and vomiting?

Nausea and vomiting occur for many reasons. Common causes include motion sickness, self-limited illnesses (viruses or food poisoning) that last a few hours to a few days, and toxins (such as certain medications).

People should consult a doctor if nausea and/or vomiting are persistent or are accompanied by other severe symptoms such as abdominal pain, fever, yellow discoloration of the skin (jaundice), or bleeding. Individuals with severe or ongoing vomiting who have other serious medical problems, are elderly, are very young, or are pregnant or nursing infants should also seek medical attention.

Motion sickness may occur in many settings including travel by car, air, or boat. This may be the best setting for the use of over-the-counter medications for nausea and vomiting. Other inner-ear problems that are related to motion sickness can create a feeling of nausea as well.

Viral infections can cause nausea...

Read the Antiemetics article »




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ondansetron-oral, Zofran Related Articles







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