olsalazine, Dipentum

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GENERIC NAME: olsalazine

BRAND NAME: Dipentum

DRUG CLASS AND MECHANISM: Olsalazine is an oral medication that works as an anti-inflammatory drug for treating inflammatory diseases of the colon. It is a derivative of salicylic acid. Inactive itself, it is converted by the bacteria in the colon to its active form, mesalamine. Following oral administration very little of the olsalazine (less than 10%) is absorbed from the intestine into the body. The benefit of mesalamine is believed to be due to a local effect from within the colon. Mesalamine also is thought to be the active component of another drug used for treating inflammatory diseases of the intestines, sulfasalazine (Azulfidine). Olsalazine was approved by the FDA in July 1990.

PRESCRIBED FOR: Olsalazine is used for maintaining remission of ulcerative colitis in patients who do not tolerate sulfasalazine.


Common side effects are:

Medically Reviewed by a Doctor on 7/23/2015

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