olanzapine, Zyprexa, Zydis, Zyprexa Relprevv

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Coping With Schizophrenia

GENERIC NAME: olanzapine

BRAND NAME: Zyprexa, Zyprexa Zydis, Zyprexa Relprevv

DRUG CLASS AND MECHANISM: Olanzapine is a drug that is used to treat schizophrenia and acute manic episodes associated with bipolar I disorder. Olanzapine belongs to a drug class known as atypical antipsychotics. Other members of this class include clozapine (Clozaril), risperidone (Risperdal), aripiprazole (Abilify) and ziprasidone (Geodon). The exact mechanism of action of olanzapine is not known. It may work by blocking receptors for several neurotransmitters (chemicals that nerves use to communicate with each other) in the brain. It binds to alpha-1, dopamine, histamine H-1, muscarinic, and serotonin type 2 (5-HT2) receptors. Olanzapine was approved by the FDA in 1996.

PRESCRIBED FOR: Olanzapine is used for treating schizophrenia and acute mixed or manic episodes associated with bipolar disorder. It also is used as maintenance therapy for bipolar disorder and treating agitation due to schizophrenia or bipolar disorder. Olanzapine also is used in combination with fluoxetine (Prozac) for treatment of resistant depression and treatment of depression associated with bipolar disorder.

Medically Reviewed by a Doctor on 1/12/2015

Quick GuideSchizophrenia Pictures Slideshow: Types, Causes, Symptoms, and Treatment

Schizophrenia Pictures Slideshow: Types, Causes, Symptoms, and Treatment
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