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- What is ofloxacin, and how does it work (mechanism of action)?
- Is ofloxacin available as a generic drug?
- Do I need a prescription for ofloxacin?
- What are the side effects of ofloxacin?
- What is the dosage for ofloxacin?
- Which drugs or supplements interact with ofloxacin?
- Is ofloxacin safe to take if I'm pregnant or breastfeeding?
- What else should I know about ofloxacin?
What is ofloxacin, and how does it work (mechanism of action)?
Ofloxacin is an antibiotic that is used to treat bacterial infections. It belongs to the fluoroquinolone class of antibiotics which includes levofloxacin (Levaquin), ciprofloxacin (Cipro), gatifloxacin (Tequin), norfloxacin (Noroxin), moxifloxacin (Avelox), trovafloxacin (Trovan) and others. Ofloxacin stops the multiplication of bacteria by inhibiting the reproduction and repair of their genetic material (DNA). The FDA approved ofloxacin in December 1990.
Is ofloxacin available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for ofloxacin?
What are the side effects of ofloxacin?
The most common side effects of ofloxacin include:
Other important side effects include symptoms of nervous system stimulation, such as:
Patients taking ofloxacin can develop skin sensitivity (photsensitivity) to direct sunlight and should avoid exposure to sunlight or use sun protection and sunscreens.
Ofloxacin as well as other antibiotics in the fluoroquinolone class of antibiotics, has been associated with tendinitis and even rupture of tendons, particularly the Achilles tendon. Some physicians recommend that patients discontinue vigorous exercise while they are taking fluoroquinolone antibiotics.
Ofloxacin should be avoided in children and adolescents under 18 years of age, as safe use in these patients have not been established.
Many antibiotics, including ofloxacin, can alter the normal bacteria in the colon and encourage overgrowth of a bacterium responsible for the development of inflammation of the colon (Clostridium difficile, pseudomembranous colitis). Pseudomembranous colitis can cause fever, abdominal pain, diarrhea, and sometimes even shock.
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