octreotide (Sandostatin, Sandostatin LAR)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Is octreotide-injection safe to take if I'm pregnant or breastfeeding?

There are no adequate and well-controlled studies of octreotide acetate use in pregnancy. There was no evidence of fetal harm in studies performed in rats and rabbits. However, as animal studies cannot be always used to predict response in humans, octreotide acetate should be used in pregnancy only if clearly needed. Octreotide acetate is classified as FDA pregnancy risk category B.

It is not known if octreotide acetate can enter breast milk. As many drugs can enter human milk and cause side effects in the nursing infant, octreotide acetate should be used cautiously during breastfeeding.

What else should I know about octreotide-injection?

What preparations of octreotide-injection are available?

  • Octreotide injection is available in ampuls and vials.
  • Ampuls containing solution for injection: 0.05, 0.1, 0.2, 0.5, and 1 mg/ml
  • Depot injection (Sandostatin LAR): 10, 20, and 30 mg per vial

How should I keep octreotide-injection stored?

  • Octreotide acetate is stored in the refrigerator between 36 F and 46 F (2 C to 8 C).
  • It should be stored in its outer carton to protect it from light.
  • If stored at room temperature, octreotide acetate is stable for 14 days if protected from light.
  • Prior to injection the solution should be allowed to warm up to room temperature.
  • The manufacturer recommends against the use of artificial means to warm up the solution.
  • Multi-dose vials should be used within 14 days of opening.
  • Ampuls are intended for single-use only and any unused portion should be discarded after opening.

REFERENCE: FDA Prescribing Information.

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