nystatin oral suspension (Mycostatin, Nilstat, Nystex)

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GENERIC NAME: nystatin oral suspension

BRAND NAME: Mycostatin, Nilstat, Nystex

DRUG CLASS AND MECHANISM: Nystatin suspension is an oral, anti-fungal liquid medication. Nystatin works by binding to sterols in the walls of fungal cells, disturbing function of the cell wall. The fungal cells eventually lose their contents, leading to their death and improvement of the fungal infection. The FDA approved Nystatin in April 1987.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Nystatin oral suspension is available as 100,000 units per 1 ml. It is available in a flavored, ready-to-use suspension form. Nystatin oral suspension is available as 60 ml or 473 ml trade sizes.

STORAGE: Nystatin is stored between 15 C to 30 C (59 F to 86 F).

PRESCRIBED FOR: Nystatin oral suspension is used for oral and throat thrush caused by the fungus, Candida albicans. It also is used for intestinal infections with Candida.

DOSING:

Children and adults: Take 4 to 6 ml by mouth four times a day. Retain the suspension in mouth as long as possible before swallowing. Continue using for at least 48 hours after symptoms disappear. The suspension should be shaken well before using.

Infants: Take 1 to 2 ml by mouth four times a day. Retain the suspension in mouth as long as possible before swallowing. Continue using for at least 48 hours after symptoms disappear. The suspension should be shaken well before using.

DRUG INTERACTIONS: There are no significant drug interactions with nystatin.

PREGNANCY: There are no adequate studies done with nystatin to determine safe and effective use in pregnant women.

NURSING MOTHERS: It is not known whether nystatin enters breast milk; therefore, it is best to be cautious before using it in nursing mothers.

SIDE EFFECTS: Side effects of nystatin are diarrhea, nausea, vomiting, rash, skin irritation, allergic reactions, and rarely Stevens-Johnson syndrome.

REFERENCES:

Medscape Drug Reference. Nystatin

Micromedex Drug Information

Nystatin - Prescribing Information


Last Editorial Review: 4/23/2014




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