Nortriptyline was approved by the FDA in November 1964.
PRESCRIBED FOR: Nortriptyline is used to elevate the mood of patients with depression.
Non-FDA approved (off-label) use of nortriptyline includes:
- Attention deficit hyperactivity disorder (ADHD) in adults, children, and adolescents as second-line therapy due to failed or partial response to other FDA-approved therapies.
Adjunctive therapy (added to other therapy) for chronic pain, for example,
- Tension headaches
- Diabetic neuropathy
- Cancer pain
- Arthritic pain
- In children <13 years old, it has been used to reduce or stop bedwetting (nocturnal enuresis)
SIDE EFFECTS: The most commonly encountered side effects associated with nortriptyline include:
- Fast heart rate
- Blurred vision
- Urinary retention
- Dry mouth
- Weight gain or loss
- Low blood pressure on standing (orthostatic hypotension)
Quick GuideDepression Hurts: Physical Symptoms of Depression
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