nortriptyline (cont.)
Combining nortriptyline or other TCAs with drugs that block acetylcholine
(anticholinergic drugs) can cause constipation and even paralyze the intestine
(paralytic ileus). Dangerous elevations in blood pressure may occur if TCA's are
combined with clonidine (Catapres, Catapres-TTS).
PREGNANCY: Safe use of nortriptyline during
pregnancy has not been
established Physicians may use nortriptyline in pregnant women if its benefits
are deemed to outweigh its potential but unknown risks.
NURSING MOTHERS: Safe use of nortriptyline during lactation has not been
established. It is not known if nortriptyline is secreted in
breast milk.
SIDE EFFECTS: The most commonly encountered side effects associated with
nortriptyline include fast heart rate, blurred vision, urinary retention, dry
mouth, constipation, weight gain or loss, and low blood pressure on standing.
Rash, hives,
seizures, and hepatitis are rare side effects. Nortriptyline also
can cause elevated pressure in the eyes of some patients with glaucoma.
Overdoses of nortriptyline can cause life-threatening abnormal heart rhythms or
seizures.
Reference: FDA Prescribing Information
Last Editorial Review: 4/15/2009
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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