norfloxacin, Noroxin

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

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Norfloxacin should be used with caution with warfarin (Coumadin) because norfloxacin can increase the risks of bleeding and bruising.

Norfloxacin should be used with caution with medications used for treating abnormal heart beats because it can affect heart rhythm.

PREGNANCY: There are no adequate studies done on norfloxacin to determine safe and effective use in pregnant women.

NURSING MOTHERS: It is not known whether norfloxacin enters breast milk; therefore, it is best to be cautious before using it in nursing mothers.

Children and adolescents: The safety and efficacy of the drug in pediatric or adolescents (under age 18) has not been established.

SIDE EFFECTS: Side effects of norfloxacin are nausea, stomach cramps, dizziness, headache, abdominal pain, diarrhea, abnormal heart beats, and photosensitivity (sun sensitivity).

Norfloxacin as well as other antibiotics in the fluoroquinolone class of antibiotics, has been associated with tendinitis and even rupture of tendons, particularly the Achilles tendon. Many antibiotics, including norfloxacin, can alter the normal bacteria in the colon and encourage overgrowth of a bacterium responsible for the development of inflammation of the colon, (C. difficile caused pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting norfloxacin (diarrhea, fever, abdominal pain, and possibly shock) should contact their doctor immediately.

Medically Reviewed by a Doctor on 10/24/2014

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